Effects of α-Synuclein Overexpression in Transgenic Caenorhabditis elegans Strains

The neural protein α-synuclein aggregates both in vivo and in vitro to form insoluble fibrils that are involved in Parkinson’s disease pathogenesis. We have generated α-synuclein/fluorescent-protein fusion constructs overexpressed in muscle cells of the nematode, Caenorhabdtis elegans. Green Fluores...

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Detalhes bibliográficos
Main Authors: Bodhicharla, Rakesh, Nagarajan, Archana, Winter, Jody, Adenle, Ademola, Nazir, Aamir, Brady, Declan, Vere, Kelly, Richens, Jo, O’Shea, Paul, Bell, David R, de Pomerai, David
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744922/
https://ncbi.nlm.nih.gov/pubmed/23244416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1871527311211080005
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