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Genetic Variation in Complex Traits in Transgenic α-Synuclein Strains of Caenorhabditis elegans
Different genetic backgrounds can modify the effect of mutated genes. Human α-synuclein (SNCA) gene encodes α-synuclein, and its oligomeric complexes accumulate with age and mediate the disruption of cellular homeostasis, resulting in the neuronal death that is characteristic of Parkinson’s Disease....
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| Опубликовано в: : | Genes (Basel) |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397059/ https://ncbi.nlm.nih.gov/pubmed/32664512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11070778 |
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