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Multi-Step Unfolding and Rearrangement of α-Lactalbumin by SDS Revealed by Stopped-Flow SAXS

Interactions between proteins and surfactants are both of fundamental interest and relevant for applications in food, cosmetics and detergency. The anionic surfactant sodium dodecyl sulfate (SDS) denatures essentially all proteins. Denaturation typically involves a number of distinct steps where gro...

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Détails bibliographiques
Publié dans:Front Mol Biosci
Auteurs principaux: Jensen, Grethe Vestergaard, Pedersen, Jannik Nedergaard, Otzen, Daniel E., Pedersen, Jan Skov
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366515/
https://ncbi.nlm.nih.gov/pubmed/32754613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00125
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