Multi-Step Unfolding and Rearrangement of α-Lactalbumin by SDS Revealed by Stopped-Flow SAXS

Interactions between proteins and surfactants are both of fundamental interest and relevant for applications in food, cosmetics and detergency. The anionic surfactant sodium dodecyl sulfate (SDS) denatures essentially all proteins. Denaturation typically involves a number of distinct steps where gro...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Jensen, Grethe Vestergaard, Pedersen, Jannik Nedergaard, Otzen, Daniel E., Pedersen, Jan Skov
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366515/
https://ncbi.nlm.nih.gov/pubmed/32754613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00125
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