Multi-Step Unfolding and Rearrangement of α-Lactalbumin by SDS Revealed by Stopped-Flow SAXS

Interactions between proteins and surfactants are both of fundamental interest and relevant for applications in food, cosmetics and detergency. The anionic surfactant sodium dodecyl sulfate (SDS) denatures essentially all proteins. Denaturation typically involves a number of distinct steps where gro...

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Publicat a:Front Mol Biosci
Autors principals: Jensen, Grethe Vestergaard, Pedersen, Jannik Nedergaard, Otzen, Daniel E., Pedersen, Jan Skov
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366515/
https://ncbi.nlm.nih.gov/pubmed/32754613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00125
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