The Thrombospondin1-TGF-β Pathway and Glaucoma

Glaucoma is characterized by abnormal remodeling of the extracellular matrix (ECM) in the trabecular meshwork and in the connective tissue beams of the lamina cribrosa (LC) at the optic nerve head (ONH), which is associated with axonal damage. Mechanical strain can stimulate ECM remodeling and incre...

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Bibliografiske detaljer
Udgivet i:J Ocul Pharmacol Ther
Main Authors: Murphy-Ullrich, Joanne E., Downs, J. Crawford
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2015
Fag:
Editorials and Commentary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366264/
https://ncbi.nlm.nih.gov/pubmed/26352161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2015.0016
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