Identification of Inhibitors of Thrombospondin 1 Activation of TGF-β

[Image: see text] TGF-β has been a target of interest for the treatment of fibrotic diseases and certain cancers. Approaches to target TGF-β include antagonists of the active ligand or TGF-β receptor kinase activity. These approaches have failed in clinical trials due to a lack of effectiveness and...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Med Chem Lett
Main Authors: Suto, Mark J., Gupta, Vandana, Mathew, Bini, Zhang, Wei, Pallero, Manuel A., Murphy-Ullrich, Joanne E.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294719/
https://ncbi.nlm.nih.gov/pubmed/32550992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00540
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki