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Thrombospondin-1 regulation of latent TGF-β activation: a therapeutic target for fibrotic disease
Transforming growth factor-β (TGF-β) is a central player in fibrotic disease. Clinical trials with global inhibitors of TGF-β have been disappointing, suggesting that a more targeted approach is warranted. Conversion of the latent precursor to the biologically active form of TGF-β represents a novel...
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| Udgivet i: | Matrix Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6015530/ https://ncbi.nlm.nih.gov/pubmed/29288716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2017.12.009 |
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