Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro

A major impediment to eliminate lymphatic filariasis and onchocerciasis is the lack of effective short-course macrofilaricidal drugs or regimens that are proven to be safe for both infections. In this study we tested oxfendazole, an anthelmintic shown to be well tolerated in phase 1 clinical trials....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Negl Trop Dis
Päätekijät: Hübner, Marc P., Martin, Coralie, Specht, Sabine, Koschel, Marianne, Dubben, Bettina, Frohberger, Stefan J., Ehrens, Alexandra, Fendler, Martina, Struever, Dominique, Mitre, Edward, Vallarino-Lhermitte, Nathaly, Gokool, Suzanne, Lustigman, Sara, Schneider, Manfred, Townson, Simon, Hoerauf, Achim, Scandale, Ivan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2020
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365463/
https://ncbi.nlm.nih.gov/pubmed/32628671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008427
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia