Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro

A major impediment to eliminate lymphatic filariasis and onchocerciasis is the lack of effective short-course macrofilaricidal drugs or regimens that are proven to be safe for both infections. In this study we tested oxfendazole, an anthelmintic shown to be well tolerated in phase 1 clinical trials....

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS Negl Trop Dis
Huvudupphovsmän: Hübner, Marc P., Martin, Coralie, Specht, Sabine, Koschel, Marianne, Dubben, Bettina, Frohberger, Stefan J., Ehrens, Alexandra, Fendler, Martina, Struever, Dominique, Mitre, Edward, Vallarino-Lhermitte, Nathaly, Gokool, Suzanne, Lustigman, Sara, Schneider, Manfred, Townson, Simon, Hoerauf, Achim, Scandale, Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365463/
https://ncbi.nlm.nih.gov/pubmed/32628671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008427
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk