Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds

Flubendazole (FBZ) is highly efficacious against filarial nematodes after parenteral administration and presents a promising macrofilaricidal drug candidate for the elimination of onchocerciasis and other filariae. In the present study the efficacy of a newly developed bioavailable amorphous solid d...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Hübner, Marc P., Ehrens, Alexandra, Koschel, Marianne, Dubben, Bettina, Lenz, Franziska, Frohberger, Stefan J., Specht, Sabine, Quirynen, Ludo, Lachau-Durand, Sophie, Tekle, Fetene, Baeten, Benny, Engelen, Marc, Mackenzie, Charles D., Hoerauf, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334906/
https://ncbi.nlm.nih.gov/pubmed/30650105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006320
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