In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis

The elimination of filarial diseases such as onchocerciasis and lymphatic filariasis is hampered by the lack of a macrofilaricidal–adult worm killing–drug. In the present study, we tested the in vivo efficacy of AN11251, a boron-pleuromutilin that targets endosymbiotic Wolbachia bacteria from filari...

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Detaylı Bibliyografya
Yayımlandı:PLoS Negl Trop Dis
Asıl Yazarlar: Ehrens, Alexandra, Lunde, Christopher S., Jacobs, Robert T., Struever, Dominique, Koschel, Marianne, Frohberger, Stefan J., Lenz, Franziska, Fendler, Martina, Turner, Joseph D., Ward, Stephen A., Taylor, Mark J., Freund, Yvonne R., Stefanakis, Rianna, Easom, Eric, Li, Xianfeng, Plattner, Jacob J., Hoerauf, Achim, Hübner, Marc P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004383/
https://ncbi.nlm.nih.gov/pubmed/31986143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007957
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