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Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1)

Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2–STEAP4)...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Oosterheert, Wout, Gros, Piet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363144/
https://ncbi.nlm.nih.gov/pubmed/32409586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013690
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