The Crystal Structure of Six-transmembrane Epithelial Antigen of the Prostate 4 (Steap4), a Ferri/Cuprireductase, Suggests a Novel Interdomain Flavin-binding Site

Steap4 is a cell surface metalloreductase linked to obesity-associated insulin resistance. Initial characterization of its cell surface metalloreductase activity has been reported, but thorough biochemical characterization of this activity is lacking. Here, we report detailed kinetic analysis of the...

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Detalhes bibliográficos
Main Authors: Gauss, George H., Kleven, Mark D., Sendamarai, Anoop K., Fleming, Mark D., Lawrence, C. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711330/
https://ncbi.nlm.nih.gov/pubmed/23733181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479154
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