Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients

AIMS : Clopidogrel is prescribed for the prevention of atherothrombotic events. While investigations have identified genetic determinants of inter-individual variability in on-treatment platelet inhibition (e.g. CYP2C19*2), evidence that these variants have clinical utility to predict major adverse...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Eur Heart J Cardiovasc Pharmacother
Main Authors: Lewis, Joshua P, Backman, Joshua D, Reny, Jean-Luc, Bergmeijer, Thomas O, Mitchell, Braxton D, Ritchie, Marylyn D, Déry, Jean-Pierre, Pakyz, Ruth E, Gong, Li, Ryan, Kathleen, Kim, Eun-Young, Aradi, Daniel, Fernandez-Cadenas, Israel, Lee, Ming Ta Michael, Whaley, Ryan M, Montaner, Joan, Gensini, Gian Franco, Cleator, John H, Chang, Kiyuk, Holmvang, Lene, Hochholzer, Willibald, Roden, Dan M, Winter, Stefan, Altman, Russ B, Alexopoulos, Dimitrios, Kim, Ho-Sook, Gawaz, Meinrad, Bliden, Kevin P, Valgimigli, Marco, Marcucci, Rossella, Campo, Gianluca, Schaeffeler, Elke, Dridi, Nadia P, Wen, Ming-Shien, Shin, Jae Gook, Fontana, Pierre, Giusti, Betti, Geisler, Tobias, Kubo, Michiaki, Trenk, Dietmar, Siller-Matula, Jolanta M, ten Berg, Jurriën M, Gurbel, Paul A, Schwab, Matthias, Klein, Teri E, Shuldiner, Alan R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363022/
https://ncbi.nlm.nih.gov/pubmed/31504375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ehjcvp/pvz045
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados