PON1 Q192R Variant and Clopidogrel Efficacy: Fact or Fiction?

Por Lewis, Joshua P., Shuldiner, Alan R.
Publicado em 2012

Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomics

Por Beitelshees, Amber L, Voora, Deepak, Lewis, Joshua P
Publicado no Pharmgenomics Pers Med (2015)

The Pharmacogenetic Control of Antiplatelet Response: Candidate Genes and CYP2C19

Por Yang, Yao, Lewis, Joshua P., Hulot, Jean-Sébastien, Scott, Stuart A.
Publicado no Expert Opin Drug Metab Toxicol (2015)

Association Analysis in African Americans of European-Derived Type 2 Diabetes Single Nucleotide Polymorphisms From Whole-Genome Association Studies

Por Lewis, Joshua P., Palmer, Nicholette D., Hicks, Pamela J., Sale, Michele M., Langefeld, Carl D., Freedman, Barry I., Divers, Jasmin, Bowden, Donald W.
Publicado em 2008

Analysis of Candidate Genes on Chromosome 20q12-13.1 Reveals Evidence for BMI Mediated Association of PREX1 with Type 2 Diabetes in European Americans

Por Lewis, Joshua P., Palmer, Nicholette D., Ellington, Jennifer B., Divers, Jasmin, Ng, Maggie C. Y., Lu, Lingyi, Langefeld, Carl D., Freedman, Barry I., Bowden, Donald W.
Publicado em 2010

Effect of Two Lipoprotein (a)-Associated Genetic Variants on Plasminogen Levels and Fibrinolysis

Por Wang, Hong, Hong, Chan E., Lewis, Joshua P., Zhu, Yanbei, Wang, Xing, Chu, Xin, Backman, Joshua, Hu, Ziying, Yang, Peixin, Still, Christopher D., Gerhard, Glenn S., Fu, Mao
Publicado no G3 (Bethesda) (2016)

The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin

Por Bozzi, Laura M., Mitchell, Braxton D., Lewis, Joshua P., Ryan, Kathy A., Herzog, William R., O’Connell, Jeffrey R., Horenstein, Richard B., Shuldiner, Alan R., Yerges-Armstrong, Laura M.
Publicado no Curr Vasc Pharmacol (2016)

Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation

Por Salimi, Shabnam, Lewis, Joshua P., Yerges‐Armstrong, Laura M., Mitchell, Braxton D., Saeed, Faisal, O'Connell, Jeffry R., Perry, James A., Ryan, Kathleen A., Shuldiner, Alan R., Parsa, Afshin
Publicado no J Am Heart Assoc (2016)

From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases

Por Tise, Christina G., Perry, James A., Anforth, Leslie E., Pavlovich, Mary A., Backman, Joshua D., Ryan, Kathleen A., Lewis, Joshua P., O’Connell, Jeffrey R., Yerges-Armstrong, Laura M., Shuldiner, Alan R.
Publicado no G3 (Bethesda) (2016)

CYP2C19 Metabolizer Status and Clopidogrel Efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) Study

Por McDonough, Caitrin W, McClure, Leslie A, Mitchell, Braxton D, Gong, Yan, Horenstein, Richard B, Lewis, Joshua P, Field, Thalia S, Talbert, Robert L, Benavente, Oscar R, Johnson, Julie A, Shuldiner, Alan R
Publicado no J Am Heart Assoc (2015)

Genome-Wide Analysis of Clopidogrel Active Metabolite Levels Identifies Novel Variants that Influence Antiplatelet Response

Por Backman, Joshua D., O’Connell, Jeffrey R., Tanner, Keith, Peer, Cody J., Figg, William D., Spencer, Shawn D., Mitchell, Braxton D., Shuldiner., Alan R., Yerges-Armstrong, Laura M., Horenstein, Richard B., Lewis, Joshua P.
Publicado no Pharmacogenet Genomics (2017)

Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction

Por Fisch, Adam S., Yerges-Armstrong, Laura M., Backman, Joshua D., Wang, Hong, Donnelly, Patrick, Ryan, Kathleen A., Parihar, Ankita, Pavlovich, Mary A., Mitchell, Braxton D., O’Connell, Jeffrey R., Herzog, William, Harman, Christopher R., Wren, Jonathan D., Lewis, Joshua P.
Publicado no PLoS One (2015)

Oxylipid Profile of Low‐Dose Aspirin Exposure: A Pharmacometabolomics Study

Por Ellero‐Simatos, Sandrine, Beitelshees, Amber L., Lewis, Joshua P., Yerges‐Armstrong, Laura M., Georgiades, Anastasia, Dane, Adrie, Harms, Amy C., Strassburg, Katrin, Guled, Faisa, Hendriks, Margriet M. W. B., Horenstein, Richard B., Shuldiner, Alan R., Hankemeier, Thomas, Kaddurah‐Daouk, Rima
Publicado no J Am Heart Assoc (2015)

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

Por Lewis, Joshua P., Horenstein, Richard B., Ryan, Kathleen, O’Connell, Jeffrey R., Gibson, Quince, Mitchell, Braxton D., Tanner, Keith, Chai, Sumbul, Bliden, Kevin P., Tantry, Udaya S., Peer, Cody J., Figg, William D., Spencer, Shawn D., Pacanowski, Michael A., Gurbel, Paul A., Shuldiner, Alan R.
Publicado em 2013

A GENOME WIDE ASSOCIATION STUDY FOR DIABETIC NEPHROPATHY GENES IN AFRICAN AMERICANS

Por McDonough, Caitrin W., Palmer, Nicholette D., Hicks, Pamela J., Roh, Bong H., An, S. Sandy, Cooke, Jessica N., Hester, Jessica M., Wing, Maria R., Bostrom, Meredith A., Rudock, Megan E., Lewis, Joshua P., Talbert, Matthew E., Blevins, Rebecca A., Lu, Lingyi, Ng, Maggie C.Y., Sale, Michele M., Divers, Jasmin, Langefeld, Carl D., Freedman, Barry I., Bowden, Donald W.
Publicado em 2010

Genetic Variation in PEAR1 is Associated with Platelet Aggregation and Cardiovascular Outcomes

Por Lewis, Joshua P., Ryan, Kathleen, O’Connell, Jeffrey R., Horenstein, Richard B., Damcott, Coleen M., Gibson, Quince, Pollin, Toni I., Mitchell, Braxton D., Beitelshees, Amber L., Pakzy, Ruth, Tanner, Keith, Parsa, Afshin, Tantry, Udaya S., Bliden, Kevin P., Post, Wendy S., Faraday, Nauder, Herzog, William, Gong, Yan, Pepine, Carl J., Johnson, Julie A., Gurbel, Paul A., Shuldiner, Alan R.
Publicado em 2013

A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans

Por Palmer, Nicholette D., McDonough, Caitrin W., Hicks, Pamela J., Roh, Bong H., Wing, Maria R., An, S. Sandy, Hester, Jessica M., Cooke, Jessica N., Bostrom, Meredith A., Rudock, Megan E., Talbert, Matthew E., Lewis, Joshua P., Ferrara, Assiamira, Lu, Lingyi, Ziegler, Julie T., Sale, Michele M., Divers, Jasmin, Shriner, Daniel, Adeyemo, Adebowale, Rotimi, Charles N., Ng, Maggie C. Y., Langefeld, Carl D., Freedman, Barry I., Bowden, Donald W.
Publicado em 2012

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

Por Walford, Geoffrey A., Gustafsson, Stefan, Rybin, Denis, Stančáková, Alena, Chen, Han, Liu, Ching-Ti, Hong, Jaeyoung, Jensen, Richard A., Rice, Ken, Morris, Andrew P., Mägi, Reedik, Tönjes, Anke, Prokopenko, Inga, Kleber, Marcus E., Delgado, Graciela, Silbernagel, Günther, Jackson, Anne U., Appel, Emil V., Grarup, Niels, Lewis, Joshua P., Montasser, May E., Landenvall, Claes, Staiger, Harald, Luan, Jian’an, Frayling, Timothy M., Weedon, Michael N., Xie, Weijia, Morcillo, Sonsoles, Martínez-Larrad, María Teresa, Biggs, Mary L., Chen, Yii-Der Ida, Corbaton-Anchuelo, Arturo, Færch, Kristine, Gómez-Zumaquero, Juan Miguel, Goodarzi, Mark O., Kizer, Jorge R., Koistinen, Heikki A., Leong, Aaron, Lind, Lars, Lindgren, Cecilia, Machicao, Fausto, Manning, Alisa K., Martín-Núñez, Gracia María, Rojo-Martínez, Gemma, Rotter, Jerome I., Siscovick, David S., Zmuda, Joseph M., Zhang, Zhongyang, Serrano-Rios, Manuel, Smith, Ulf, Soriguer, Federico, Hansen, Torben, Jørgensen, Torben J., Linnenberg, Allan, Pedersen, Oluf, Walker, Mark, Langenberg, Claudia, Scott, Robert A., Wareham, Nicholas J., Fritsche, Andreas, Häring, Hans-Ulrich, Stefan, Norbert, Groop, Leif, O’Connell, Jeff R., Boehnke, Michael, Bergman, Richard N., Collins, Francis S., Mohlke, Karen L., Tuomilehto, Jaakko, März, Winfried, Kovacs, Peter, Stumvoll, Michael, Psaty, Bruce M., Kuusisto, Johanna, Laakso, Markku, Meigs, James B., Dupuis, Josée, Ingelsson, Erik, Florez, Jose C.
Publicado no Diabetes (2016)