Genetic Variation in PEAR1 is Associated with Platelet Aggregation and Cardiovascular Outcomes

BACKGROUND: Aspirin or dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard therapy for patients at increased risk for cardiovascular events. However, the genetic determinants of variable response to aspirin (alone and in combination with clopidogrel) are not known. METHODS AND...

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Detalhes bibliográficos
Main Authors: Lewis, Joshua P., Ryan, Kathleen, O’Connell, Jeffrey R., Horenstein, Richard B., Damcott, Coleen M., Gibson, Quince, Pollin, Toni I., Mitchell, Braxton D., Beitelshees, Amber L., Pakzy, Ruth, Tanner, Keith, Parsa, Afshin, Tantry, Udaya S., Bliden, Kevin P., Post, Wendy S., Faraday, Nauder, Herzog, William, Gong, Yan, Pepine, Carl J., Johnson, Julie A., Gurbel, Paul A., Shuldiner, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715320/
https://ncbi.nlm.nih.gov/pubmed/23392654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.964627
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