Genetic Variation in PEAR1 is Associated with Platelet Aggregation and Cardiovascular Outcomes

BACKGROUND: Aspirin or dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard therapy for patients at increased risk for cardiovascular events. However, the genetic determinants of variable response to aspirin (alone and in combination with clopidogrel) are not known. METHODS AND...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lewis, Joshua P., Ryan, Kathleen, O’Connell, Jeffrey R., Horenstein, Richard B., Damcott, Coleen M., Gibson, Quince, Pollin, Toni I., Mitchell, Braxton D., Beitelshees, Amber L., Pakzy, Ruth, Tanner, Keith, Parsa, Afshin, Tantry, Udaya S., Bliden, Kevin P., Post, Wendy S., Faraday, Nauder, Herzog, William, Gong, Yan, Pepine, Carl J., Johnson, Julie A., Gurbel, Paul A., Shuldiner, Alan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715320/
https://ncbi.nlm.nih.gov/pubmed/23392654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.964627
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