Paraoxonase 1 (PON1) Gene Variants Are Not Associated With Clopidogrel Response

A common functional variant in paraoxonase 1 (PON1), Q192R, was recently reported to be a major determinant of clopidogrel response. This variant was genotyped in 566 participants of the Amish Pharmacogenomics of Anti-Platelet Intervention (PAPI) study and in 227 percutaneous coronary intervention (...

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Detalhes bibliográficos
Main Authors: Lewis, JP, Fisch, AS, Ryan, K, O’Connell, JR, Gibson, Q, Mitchell, BD, Shen, H, Tanner, K, Horenstein, RB, Pakzy, R, Tantry, US, Bliden, KP, Gurbel, PA, Shuldiner, AR
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250350/
https://ncbi.nlm.nih.gov/pubmed/21881565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2011.194
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