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Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel

Ticagrelor (TIC), a P2Y purinoceptor 12 (P2Y(12))-receptor antagonist, has been widely used to treat patients with acute coronary syndrome. Although animal studies suggest that TIC protects against atherosclerosis, it remains unknown whether it does so through its potent platelet inhibition or throu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Halim, Hasseri, Pinkaew, Decha, Chunhacha, Preedakorn, Sinthujaroen, Patuma, Thiagarajan, Perumal, Fujise, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594647/
https://ncbi.nlm.nih.gov/pubmed/31242230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218934
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