Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel

Ticagrelor (TIC), a P2Y purinoceptor 12 (P2Y(12))-receptor antagonist, has been widely used to treat patients with acute coronary syndrome. Although animal studies suggest that TIC protects against atherosclerosis, it remains unknown whether it does so through its potent platelet inhibition or throu...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Halim, Hasseri, Pinkaew, Decha, Chunhacha, Preedakorn, Sinthujaroen, Patuma, Thiagarajan, Perumal, Fujise, Ken
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594647/
https://ncbi.nlm.nih.gov/pubmed/31242230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218934
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