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Genetic Variation in PEAR1 is Associated with Platelet Aggregation and Cardiovascular Outcomes

BACKGROUND: Aspirin or dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard therapy for patients at increased risk for cardiovascular events. However, the genetic determinants of variable response to aspirin (alone and in combination with clopidogrel) are not known. METHODS AND...

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主要な著者: Lewis, Joshua P., Ryan, Kathleen, O’Connell, Jeffrey R., Horenstein, Richard B., Damcott, Coleen M., Gibson, Quince, Pollin, Toni I., Mitchell, Braxton D., Beitelshees, Amber L., Pakzy, Ruth, Tanner, Keith, Parsa, Afshin, Tantry, Udaya S., Bliden, Kevin P., Post, Wendy S., Faraday, Nauder, Herzog, William, Gong, Yan, Pepine, Carl J., Johnson, Julie A., Gurbel, Paul A., Shuldiner, Alan R.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715320/
https://ncbi.nlm.nih.gov/pubmed/23392654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.964627
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