Genome-Wide Analysis of Clopidogrel Active Metabolite Levels Identifies Novel Variants that Influence Antiplatelet Response

Clopidogrel is one of the most commonly used therapeutics for secondary prevention of cardiovascular events in patients with acute coronary syndromes. However, substantial inter-individual variation in clopidogrel response has been documented, resulting in suboptimal therapy and an increased risk of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacogenet Genomics
Prif Awduron: Backman, Joshua D., O’Connell, Jeffrey R., Tanner, Keith, Peer, Cody J., Figg, William D., Spencer, Shawn D., Mitchell, Braxton D., Shuldiner., Alan R., Yerges-Armstrong, Laura M., Horenstein, Richard B., Lewis, Joshua P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346037/
https://ncbi.nlm.nih.gov/pubmed/28207573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000272
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