A Sensitive and Rapid Ultra HPLC-MS/MS Method for the Simultaneous Detection of Clopidogrel and its Derivatized Active Thiol Metabolite in Human Plasma

A sensitive, selective, and rapid ultra-high performance liquid chromatography-tandem mass spectrometry (uHPLC-MS/MS) was developed for the simultaneous quantification of clopidogrel (Plavix(®)) and its derivatized active metabolite (CAMD) in human plasma. Derivatization of the active metabolite in...

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Detalhes bibliográficos
Main Authors: Peer, Cody J., Spencer, Shawn D., VanDenBerg, Dustin A. H., Pacanowski, Michael A., Horenstein, Richard B., Figg, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246081/
https://ncbi.nlm.nih.gov/pubmed/22169056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.11.029
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