Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium

Antiplatelet response to clopidogrel shows wide variation, and poor response is correlated with adverse clinical outcomes. CYP2C19 loss‐of‐function alleles play an important role in this response, but account for only a small proportion of variability in response to clopidogrel. An aim of the Intern...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Verma, Shefali Setia, Bergmeijer, Thomas O., Gong, Li, Reny, Jean‐Luc, Lewis, Joshua P., Mitchell, Braxton D., Alexopoulos, Dimitrios, Aradi, Daniel, Altman, Russ B., Bliden, Kevin, Bradford, Yuki, Campo, Gianluca, Chang, Kiyuk, Cleator, John H., Déry, Jean‐Pierre, Dridi, Nadia P., Fernandez‐Cadenas, Israel, Fontana, Pierre, Gawaz, Meinrad, Geisler, Tobias, Gensini, Gian Franco, Giusti, Betti, Gurbel, Paul A., Hochholzer, Willibald, Holmvang, Lene, Kim, Eun‐Young, Kim, Ho‐Sook, Marcucci, Rossella, Montaner, Joan, Backman, Joshua D., Pakyz, Ruth E., Roden, Dan M., Schaeffeler, Elke, Schwab, Matthias, Shin, Jae Gook, Siller‐Matula, Jolanta M., ten Berg, Jurriën M., Trenk, Dietmar, Valgimigli, Marco, Wallace, John, Wen, Ming‐Shien, Kubo, Michiaki, Lee, Ming Ta Michael, Whaley, Ryan, Winter, Stefan, Klein, Teri E., Shuldiner, Alan R., Ritchie, Marylyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689744/
https://ncbi.nlm.nih.gov/pubmed/32472697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1911
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