Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions

The role of glycoprotein VI (GPVI) in platelets was investigated in 3 families bearing an insertion within the GP6 gene that introduces a premature stop codon prior to the transmembrane domain, leading to expression of a truncated protein in the cytoplasm devoid of the transmembrane region. Western...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Nagy, Magdolna, Perrella, Gina, Dalby, Amanda, Becerra, M. Francisca, Garcia Quintanilla, Lourdes, Pike, Jeremy A., Morgan, Neil V., Gardiner, Elizabeth E., Heemskerk, Johan W. M., Azócar, Lorena, Miquel, Juan Francisco, Mezzano, Diego, Watson, Steve P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362345/
https://ncbi.nlm.nih.gov/pubmed/32603422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001761
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