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Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs

Platelets engage cues of pending vascular injury through coordinated adhesion, secretion, and aggregation responses. These rapid, progressive changes in platelet form and function are orchestrated downstream of specific receptors on the platelet surface and through intracellular signaling mechanisms...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Babur, Özgün, Melrose, Alexander R., Cunliffe, Jennifer M., Klimek, John, Pang, Jiaqing, Sepp, Anna-Liisa I., Zilberman-Rudenko, Jevgenia, Tassi Yunga, Samuel, Zheng, Tony, Parra-Izquierdo, Iván, Minnier, Jessica, McCarty, Owen J. T., Demir, Emek, Reddy, Ashok P., Wilmarth, Phillip A., David, Larry L., Aslan, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702475/
https://ncbi.nlm.nih.gov/pubmed/32640021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005496
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