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Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions

Thymidine triphosphate bearing benzylidene‐tetrahydroxanthylium near‐IR fluorophore linked to the 5‐methyl group via triazole was synthesized through the CuAAC reaction and was used for polymerase synthesis of labelled DNA probes. The fluorophore lights up upon incorporation to DNA (up to 348‐times)...

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Библиографические подробности
Опубликовано в: :Chemistry
Главные авторы: Kuba, Miroslav, Kraus, Tomáš, Pohl, Radek, Hocek, Michal
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361531/
https://ncbi.nlm.nih.gov/pubmed/32633433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202003192
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