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Metallo-Phthalocyanine Near-IR Fluorophores: Oligonucleotide Conjugates and Their Applications in PCR Assays

Water soluble, metallo-pthalocyanine (MPc) near-IR fluorophores were designed, synthesized, and evaluated as highly stable and sensitive reporters for fluorescence assays. Their conjugation to oligonucleotides was achieved via succinimidyl ester-amino coupling chemistry with the conditions for conju...

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Библиографические подробности
Главные авторы: Nesterova, Irina V., Verdree, Vera T., Pakhomov, Serhii, Strickler, Karen L., Allen, Michael W., Hammer, Robert P., Soper, Steven A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024546/
https://ncbi.nlm.nih.gov/pubmed/18030995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc700233w
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