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Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions

Thymidine triphosphate bearing benzylidene‐tetrahydroxanthylium near‐IR fluorophore linked to the 5‐methyl group via triazole was synthesized through the CuAAC reaction and was used for polymerase synthesis of labelled DNA probes. The fluorophore lights up upon incorporation to DNA (up to 348‐times)...

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Bibliografiske detaljer
Udgivet i:Chemistry
Main Authors: Kuba, Miroslav, Kraus, Tomáš, Pohl, Radek, Hocek, Michal
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361531/
https://ncbi.nlm.nih.gov/pubmed/32633433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202003192
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