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Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions

Thymidine triphosphate bearing benzylidene‐tetrahydroxanthylium near‐IR fluorophore linked to the 5‐methyl group via triazole was synthesized through the CuAAC reaction and was used for polymerase synthesis of labelled DNA probes. The fluorophore lights up upon incorporation to DNA (up to 348‐times)...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Kuba, Miroslav, Kraus, Tomáš, Pohl, Radek, Hocek, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361531/
https://ncbi.nlm.nih.gov/pubmed/32633433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202003192
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