An Unusual MHC Molecule Generates Protective CD8+ T Cell Responses to Chronic Infection

The CD8+ T cell response to the intracellular parasite Toxoplasma gondii varies dramatically between mouse strains, resulting in stark differences in control of the parasite. Protection in BALB/c mice can be attributed to an unusually strong and protective MHC-1 L(d)-restricted CD8+ T cell response...

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Udgivet i:Front Immunol
Main Authors: Tsitsiklis, Alexandra, Bangs, Derek J., Lutes, Lydia K., Chan, Shiao W., Geiger, Kristina M., Modzelewski, Andrew J., Labarta-Bajo, Lara, Wang, Yang, Zuniga, Elina I., Dai, Shaodong, Robey, Ellen A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360836/
https://ncbi.nlm.nih.gov/pubmed/32733483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01464
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