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TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections
Suppression of CD8 and CD4 T cells is a hallmark in chronic viral infections, including hepatitis C and HIV. While multiple pathways are known to inhibit CD8 T cells, the host molecules that restrict CD4 T cell responses are less understood. Here, we used inducible and CD4 T cell–specific deletion o...
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| Pubblicato in: | J Clin Invest |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096797/ https://ncbi.nlm.nih.gov/pubmed/27599295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87041 |
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