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TGF-β1 maintains suppressor function and Foxp3 expression in CD4(+)CD25(+) regulatory T cells

Transforming growth factor (TGF)-β1 is a major pluripotential cytokine with a pronounced immunosuppressive effect and its deficiency results in lethal autoimmunity in mice. However, mechanisms of its immunosuppressive action are not completely understood. Here, we report that TGF-β1 supports the mai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marie, Julien C., Letterio, John J., Gavin, Marc, Rudensky, Alexander Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213134/
https://ncbi.nlm.nih.gov/pubmed/15809351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042276
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