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Increase in TGF-β Secreting CD4(+)CD25(+) FOXP3(+) T Regulatory Cells in Anergic Lepromatous Leprosy Patients
BACKGROUND: Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T cell unresponsiveness/anergy whose underlying mechanisms are not fully defined. We investigated the role of CD25(+)FOXP3(+) regulatory T cells in both skin lesions and M.leprae stimulated PBMC cultur...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894184/ https://ncbi.nlm.nih.gov/pubmed/24454972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002639 |
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