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TGF-β regulates in vivo expansion of Foxp3-expressing CD4(+)CD25(+) regulatory T cells responsible for protection against diabetes

CD4(+)CD25(+) regulatory T cells are essential in the protection from organ-specific autoimmune diseases. In the pancreas, they inhibit actions of autoreactive T cells and thereby prevent diabetes progression. The signals that control the generation, the maintenance, or the expansion of regulatory T...

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Bibliografiske detaljer
Main Authors: Peng, Yufeng, Laouar, Yasmina, Li, Ming O., Green, E. Allison, Flavell, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384788/
https://ncbi.nlm.nih.gov/pubmed/15070759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400810101
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