TGF-β regulates in vivo expansion of Foxp3-expressing CD4(+)CD25(+) regulatory T cells responsible for protection against diabetes

CD4(+)CD25(+) regulatory T cells are essential in the protection from organ-specific autoimmune diseases. In the pancreas, they inhibit actions of autoreactive T cells and thereby prevent diabetes progression. The signals that control the generation, the maintenance, or the expansion of regulatory T...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Peng, Yufeng, Laouar, Yasmina, Li, Ming O., Green, E. Allison, Flavell, Richard A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2004
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15070759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400810101
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