CD4(+)FoxP3(+) regulatory T cells confer infectious tolerance in a TGF-β–dependent manner

CD4(+)FoxP3(+) regulatory T (T reg) cells comprise a separate lineage of T cells that are essential for maintaining immunological tolerance to self. The molecular mechanism(s) by which T reg cells mediate their suppressive effects remains poorly understood. One molecule that has been extensively stu...

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Autores principales: Andersson, John, Tran, Dat Q., Pesu, Marko, Davidson, Todd S., Ramsey, Heather, O'Shea, John J., Shevach, Ethan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
Materias:
Brief Definitive Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526184/
https://ncbi.nlm.nih.gov/pubmed/18710931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080308
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