GARP (LRRC32) is essential for the surface expression of latent TGF-β on platelets and activated FOXP3(+) regulatory T cells

TGF-β family members are highly pleiotropic cytokines with diverse regulatory functions. TGF-β is normally found in the latent form associated with latency-associated peptide (LAP). This latent complex can associate with latent TGFβ-binding protein (LTBP) to produce a large latent form. Latent TGF-β...

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Detaylı Bibliyografya
Asıl Yazarlar: Tran, Dat Q., Andersson, John, Wang, Rui, Ramsey, Heather, Unutmaz, Derya, Shevach, Ethan M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726354/
https://ncbi.nlm.nih.gov/pubmed/19651619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901944106
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