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Regulation of the expression of GARP/latent-TGF-β1 complexes on mouse T cells and their role in Regulatory T Cell and Th17 differentiation()

GARP/LRRC32 has previously been defined as a marker of activated human regulatory T-cells (Tregs) that is responsible for surface localization of latent TGF-β1. We find that GARP and latent TGF-β1 are also found on mouse Tregs activated via TCR stimulation, but in contrast to human Tregs, GARP is al...

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Detalhes bibliográficos
Main Authors: Edwards, Justin P., Fujii, Hodaka, Zhou, Angela X., Creemers, John, Unutmaz, Derya, Shevach, Ethan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668701/
https://ncbi.nlm.nih.gov/pubmed/23645881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300199
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