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Release of active TGF-β1 from the Latent TGF-β1/GARP complex on T regulatory cells is mediated by Integrin β8()

Activated T regulatory cells (Treg) express latent TGF-β1 on their cell surface bound to GARP. Although integrins have been implicated in mediating the release of active TGF-β1 from the complex of latent TGF-β1 and latent TGF-β1 binding protein, their role in processing latent TGF-β1 from the latent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Edwards, Justin P., Thornton, Angela M., Shevach, Ethan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157079/
https://ncbi.nlm.nih.gov/pubmed/25127859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401102
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