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GARP (LRRC32) is essential for the surface expression of latent TGF-β on platelets and activated FOXP3(+) regulatory T cells
TGF-β family members are highly pleiotropic cytokines with diverse regulatory functions. TGF-β is normally found in the latent form associated with latency-associated peptide (LAP). This latent complex can associate with latent TGFβ-binding protein (LTBP) to produce a large latent form. Latent TGF-β...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2726354/ https://ncbi.nlm.nih.gov/pubmed/19651619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901944106 |
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