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TCRα reporter mice reveal contribution of dual TCRα expression to T cell repertoire and function

It is known that a subpopulation of T cells expresses two T cell receptor (TCR) clonotypes, though the extent and functional significance of this is not established. To definitively evaluate dual TCRα cells, we generated mice with green fluorescent protein and red fluorescent protein reporters linke...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yang, Letitia, Jama, Burhan, Wang, Huawei, Labarta-Bajo, Lara, Zúñiga, Elina I., Morris, Gerald P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768769/
https://ncbi.nlm.nih.gov/pubmed/33288689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013188117
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