Paired analysis of TCRα and TCRβ chains at the single-cell level in mice

Characterizing the TCRα and TCRβ chains expressed by T cells responding to a given pathogen or underlying autoimmunity helps in the development of vaccines and immunotherapies, respectively. However, our understanding of complementary TCRα and TCRβ chain utilization is very limited for pathogen- and...

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Detalhes bibliográficos
Main Authors: Dash, Pradyot, McClaren, Jennifer L., Oguin, Thomas H., Rothwell, William, Todd, Brandon, Morris, Melissa Y., Becksfort, Jared, Reynolds, Cory, Brown, Scott A., Doherty, Peter C., Thomas, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007160/
https://ncbi.nlm.nih.gov/pubmed/21135507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44752
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