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Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer

DNA repair genes are commonly altered in metastatic prostate cancer, but BRCA1 mutations are rare. Preliminary studies suggest that higher tumor expression of the BRCA1 protein may be associated with worse prognosis. We undertook a prospective study among men with prostate cancer in the Health Profe...

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Publicado en:Carcinogenesis
Main Authors: Stopsack, Konrad H, Gerke, Travis, Zareba, Piotr, Pettersson, Andreas, Chowdhury, Dipanjan, Ebot, Ericka M, Flavin, Richard, Finn, Stephen, Kantoff, Philip W, Stampfer, Meir J, Loda, Massimo, Fiorentino, Michelangelo, Mucci, Lorelei A
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359768/
https://ncbi.nlm.nih.gov/pubmed/32556091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa061
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