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A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer

BACKGROUND: PTEN is a tumor suppressor frequently deleted in prostate cancer that may be a useful prognostic biomarker. However, the association of PTEN loss with lethal disease has not been tested in a large, predominantly surgically treated cohort. METHODS: In the Health Professionals Follow-up St...

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Publicat a:J Natl Cancer Inst
Autors principals: Ahearn, Thomas U., Pettersson, Andreas, Ebot, Ericka M., Gerke, Travis, Graff, Rebecca E., Morais, Carlos L., Hicks, Jessica L., Wilson, Kathryn M., Rider, Jennifer R., Sesso, Howard D., Fiorentino, Michelangelo, Flavin, Richard, Finn, Stephen, Giovannucci, Edward L., Loda, Massimo, Stampfer, Meir J., De Marzo, Angelo M., Mucci, Lorelei A., Lotan, Tamara L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862436/
https://ncbi.nlm.nih.gov/pubmed/26615022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv346
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