A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer

BACKGROUND: PTEN is a tumor suppressor frequently deleted in prostate cancer that may be a useful prognostic biomarker. However, the association of PTEN loss with lethal disease has not been tested in a large, predominantly surgically treated cohort. METHODS: In the Health Professionals Follow-up St...

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Pubblicato in:J Natl Cancer Inst
Autori principali: Ahearn, Thomas U., Pettersson, Andreas, Ebot, Ericka M., Gerke, Travis, Graff, Rebecca E., Morais, Carlos L., Hicks, Jessica L., Wilson, Kathryn M., Rider, Jennifer R., Sesso, Howard D., Fiorentino, Michelangelo, Flavin, Richard, Finn, Stephen, Giovannucci, Edward L., Loda, Massimo, Stampfer, Meir J., De Marzo, Angelo M., Mucci, Lorelei A., Lotan, Tamara L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862436/
https://ncbi.nlm.nih.gov/pubmed/26615022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv346
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