Pre-diagnostic circulating sex hormone levels and risk of prostate cancer by ERG tumour protein expression

BACKGROUND: Experimental studies have shown androgen receptor stimulation to facilitate formation of the TMPRSS2:ERG gene fusion in prostate cell lines. No study has tested whether higher pre-diagnostic circulating sex hormone levels in men increase risk of developing TMPRSS2:ERG-positive prostate c...

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Vydáno v:Br J Cancer
Hlavní autoři: Graff, Rebecca E, Meisner, Allison, Ahearn, Thomas U, Fiorentino, Michelangelo, Loda, Massimo, Giovannucci, Edward L, Mucci, Lorelei A, Pettersson, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Genetics and Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984801/
https://ncbi.nlm.nih.gov/pubmed/26986253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.61
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