Immunohistochemical expression of BRCA1 and lethal prostate cancer

BRCA1 functions as a tumor suppressor; recent work suggests that BRCA1 may also induce cell-cycle arrest to allow for DNA repair. We hypothesized that BRCA1 expression in prostate tumor tissue may be associated with prostate cancer progression through regulation of the cell-cycle. We used immunohist...

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Detalhes bibliográficos
Main Authors: Fiorentino, Michelangelo, Judson, Gregory, Penney, Kathryn, Flavin, Richard, Stark, Jennifer, Fiore, Christopher, Fall, Katja, Martin, Neil, Ma, Jing, Sinnott, Jennifer, Giovannucci, Edward, Stampfer, Meir, Sesso, Howard D., Kantoff, Philip W., Finn, Stephen, Loda, Massimo, Mucci, Lorelei
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049266/
https://ncbi.nlm.nih.gov/pubmed/20388772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4100
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