Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription

Sperm contributes genetic and epigenetic information to the embryo to efficiently support development. However, the mechanism underlying such developmental competence remains elusive. Here, we investigated whether all sperm cells have a common epigenetic configuration that primes transcriptional pro...

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Pubblicato in:Nat Commun
Autori principali: Oikawa, Mami, Simeone, Angela, Hormanseder, Eva, Teperek, Marta, Gaggioli, Vincent, O’Doherty, Alan, Falk, Emma, Sporniak, Matthieu, D’Santos, Clive, Franklin, Valar Nila Roamio, Kishore, Kamal, Bradshaw, Charles R., Keane, Declan, Freour, Thomas, David, Laurent, Grzybowski, Adrian T., Ruthenburg, Alexander J., Gurdon, John, Jullien, Jerome
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359334/
https://ncbi.nlm.nih.gov/pubmed/32661239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17238-w
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