Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription

Sperm contributes genetic and epigenetic information to the embryo to efficiently support development. However, the mechanism underlying such developmental competence remains elusive. Here, we investigated whether all sperm cells have a common epigenetic configuration that primes transcriptional pro...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Oikawa, Mami, Simeone, Angela, Hormanseder, Eva, Teperek, Marta, Gaggioli, Vincent, O’Doherty, Alan, Falk, Emma, Sporniak, Matthieu, D’Santos, Clive, Franklin, Valar Nila Roamio, Kishore, Kamal, Bradshaw, Charles R., Keane, Declan, Freour, Thomas, David, Laurent, Grzybowski, Adrian T., Ruthenburg, Alexander J., Gurdon, John, Jullien, Jerome
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359334/
https://ncbi.nlm.nih.gov/pubmed/32661239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17238-w
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